MEDLINE e25. Levitt M Faiman C Hawks R Wilson A: Randomized double blind comparison of delta-9-tetrahydroicannabinol (THC) and marijuana as chemotherapy antiemetics. Proc Am Soc Clin Oncol 1984; 3: 91.
Artim R DiBella N: Tetrahydrocannabinol (THC) plus prochlorperazine (PCZ) for refractory nausea and vomiting (N/V). Cbd Cannabis Oil Buy proc Am Soc Clin Oncol 1983; 2: 84. e17. Chang AE Shiling DJ Stillman RC Goldberg NH Seipp CA Barofsky I: Delta-9-tetrahydrocannabinol as an antiemetics in cancer patients receiving high-dose
CrossRef MEDLINE PubMed Central 10. Grotenhermen F: Cannabinoids. Curr Drug Targets CNS Neurol Disord 2005; 4: 507-30. CrossRef MEDLINE 11. 12.
Lambert DM: Cannabinoids in Nature and Medicine. Weinheim: Wiley-Vch. Verlag GmbH & Co.
CrossRef MEDLINE 17. Moore TH Zammit S Lingford-Hughes A et al.: Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet 2007; 370: 319-28. CrossRef MEDLINE 18. Hzode C Zafrani ES Roudot-Thoraval F et al.
Jones SE Durant JR Greco FA Robertone A: A multi-institutional phase III study of nabilone vs placebo in chemotherapy-induced nausea and vomiting. Can Treat Rev 1982; 9: 45-8. CrossRef MEDLINE e46. Levitt M: Nabilone vs placebo in the treatment of chemotherapy-induced nausea and vomiting in cancer patients. Can Treat Rev 1982; 9(suppl B): 49-53. CrossRef MEDLINE e47.
MEDLINE e58. e59. Struwe M Kaempfer SH Geiger CJ et al.: Effect of cbd nausea dronabinol on nutritional status in HIV infection. Ann Pharmacother 1993; 27: 827-31. MEDLINE e60.
Hirvonen J Goodwin RS Li CT et al.: Reversible and regionally selective down regulation of brain cannabinoid CB(1) receptors in chronic daily cannabis smokers. Molecular Psychiatry 2012; 17 642-49 MEDLINE e117. Kurzthaler I Bodner T Kemmler G et al.
Metabolites can be stored in fatty tissues and re-released over time (up to weeks); Cbd Cannabis Oil Buy one metabolite of THC is pharmacologically active (11-hydroxy-THC). Further metabolism occurs in renal and biliary systems. Half-life: Bi-exponential half-lives with short initial phases of Cannabidiol- 1.4-1.8 hr; THC- 1.3-1.7 hr11-hydroxy-THC- 1.9-2.1 hr; terminal elimination half-life of cannabinoids- 24-26 hr or more. TIME/ACTION PROFILE (analgesic and antispasticity effects) cannabidiol unknown ?Blood levels peak more quickly when administered under the tongue. Contraindication/Precautions History of schizophrenia/psychoses; Patients with child-bearing potential who are not using reliable contraception; Sore/inflamed mucosa (may alter absorption); OB: Pregnancy (avoid use); Lactation: Avoid breast-feeding (Cannabinoids enter breast milk in considerable amounts); Pedi: Safe and effective use in children <18 yr has not been established; avoid use.
Clin Pharmacol Ther 1978; 24: 223-7 MEDLINE e90. Blake DR Robson P Ho M Jubb RW McCabe CS: Preliminary assessment of the efficacy tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology 2006; 45: 50-2 CrossRef MEDLINE e91. Skrabek RQ Galimova L Ethans K Perry D: Nabilone for the treatment of pain in fibromyalgia. J Pain 2008; 9: 164-73 MEDLINE hemp oil milk paint e92. Ware MA Fitzcharles MA Joseph L
Shir Y: The effects of nabilone on sleep in fibromyalgia: results of a randomized controlled trial.
Efficacy and tolerability of high-dose dronabinol maintenance in HIV-positive marijuana smokers: a controlled laboratory study. Psychopharmacology 2010; 212: 675-86. MEDLINE e63. Abrams DI Hilton JF Leiser RJ et al.
The next most common physical symptom is night sweats sometimes to the point of having to change night clothes. They can last from a few nights to a month or so. Sweating is one of the body’s natural ways of getting rid of toxins. Hand sweats are very common and are often accompanied by an unpleasant smell from the hands. Body odor is enough in many instances to require extra showers or baths.
MEDLINE PubMed Central e41. Einhorn LH Nagy C Furnas B Williams SD: Nabilone: an effective antiemetic in patients receiving cancer chemotherapy. J Clin Pharmacol 1981; 21(8-9 Suppl): 64-9. MEDLINE e42. e43. Herman TS Einhorn LH Jones SE et al.
N Engl J Med 1975; 293: 795-7. CrossRef MEDLINE e32. Ungerleider JT Andrysiak T Fairbanks L Goodnight J Sarna G Jamison
K: Cannabis and cancer chemotherapy. A comparison of oral delta-9-THC and prochlorperazine. Cancer 1982; 50: 636-45. MEDLINE e33.
Zajicek JP Sanders HP Wright DE et al.: Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow up. J Neurol Neurosurg Psychiatry 2005; 76: 1664-9. MEDLINE e7. Vaney C Heinzel-Gutenbrunner M Jobin P et al.: Efficacy safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized double-blind placebo-controlled crossover study. Multiple Sclerosis 2004; 10: 417-24. MEDLINE e8. Wade DT Makela P Robson P House H Bateman C: Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple cbd medical west perth sclerosis? A cbd oil anxiety dosage double-blind randomized placebo-controlled study on 160 patients.
Grotenhermen F: The toxicology of cannabis and cannabis prohibition. Chem Biodivers 2007; 4: 1744-69. CrossRef 15.