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The column was re-equilibrated under initial conditions for 4min. Flow-rate was 0.5ml/min and injection volume was 2?l. Eluted compounds were detected at a wavelength of 228nm. All determinations were carried out at a column cbd yummy smoke report temperature of 40C. The HPLC method used was previously described ( 11 ; adapted in 17 ) and validated again here.
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